UMAIR ALI KHAN

SADDOZAI

SCHOOL OF BASIC MEDICINE

HENAN UNIVERSITY CHINA

Umairsaddozai2@gmail.com

OBJECTIVE

To become a good researcher, motivate those who work under my supervision and get motivation from whom I am being supervised.

 EDUCATION

Cell biology, Doctor of Philosophy (PhD) 2018 – To date

Henan University, Pakistan (http://www.henu.edu.cn)

Studies focused on different Cancers.

Biotechnology, Master of Philosophy (MPhil) 2017

Gomal University, Pakistan (http://www.gu.edu.pk)

Studies focused on biofilms formation, observation, structures and use of novel medicinal plant and their synergistic effect with medicine against different Microbial Biofilms.

Biotechnology, BS (Hons) 2007 – 2012

Gomal University, Pakistan (http://www.gu.edu.pk)

Specialized in communication and handling of different microbial techniques.

Pre-Medical, Government Degree College No.1 2005

Studies focused in medical subjects such as Botany, Zoology, Physics and Chemistry. Learned basic concepts and applied these concepts to practical issues.

Research Interests

ß Human cancers

ß Bioinformatics

ß Genetic disease

ß Development of biomedical database

ß Bacterial Biofilms

ß Biology of Micro-organisms

ß Immunology

ß Medical biotechnology

ß Microbial Diversity

ß Post translation modification

ß Cell signaling

ß Environmental preservation

PROJECTS

Analysis of Human cancers with advanced Bioinformatics tools.

Doctor of philosophy research focuses on the study of human cancers, genetic disease and development of biomedical databases/software by using high-throughput and high dimension data, my goal is to molecularly subtype diseases and build subtype-specific diagnostic and prognostic biomarkers, and to identify potential subtype-specific therapeutic targets.

Biofilm detection, production and inhibition by using medicinal plants as Antimicrobial agents.

MPhil degree thesis is on biofilm detection and inhibition by using different medicinal plants. Different techniques were used to produce biofilm of multiple strains. After successful production of biofilm, number of novel plants were used alone and their synergy with Antibiotics to eradicate biofilm. The effect of plant extracts and their synergy was also checked during biofilm production.

 SKILLS

• Human cell culture techniques

• Data sciences

• Biomedical Database production

• Gene pattern analysis

• Gene Ontology

• Genes Overexpression

• Targeted databases

• Cancer Subtypes specificity analysis

• GSEA analysis

• Bacterial biofilms detection and production

• Anaerobic culturing

• Analysis of bacterial sequence

• Lectin and DNA staining

• Biochemical analysis of acid and enzyme on organic matter

• Maintenance of required culture

• Conducting site micro awareness trainings

• Biochemical Test for Screening of Microbes

• Staining (endospore, capsular, flagellar, fungal staining and gram staining for bacteria

• Antibiotics Sensitivity Test

• Thin layer and paper chromatography

• ELISA and immunodiffusion assays

• Flow Cytometry

 LANGUAGE PROFICIENCY

Good command over English language as well as on Chinese, Urdu, Hindi, Punjabi and Saraiki.

CO-CURRICULUM ACTIVITIES

Participated in various college activities like member of the decoration committee during college function and participated in poster presentation at college level.

STRENGTH

• Profound ability to work individually and in a team

• Able to work additional hours if required

• Outstanding physical and mental dexterity

• Expert to handle bioinformatics software’s

• Excellent grasp of microbiological terminology

• Self-directed and organized

• Willingness to learn and follow directions

Publications

Saddozai, UAK, Wang F, Cheng Y, Lu, Z, Akbar MU, Zhu W, Li Y, Ji, Xin-Ying and Guo X. (2020). Gene expression profile identifies distinct molecular subtypes and potential therapeutic genes in Merkel cell carcinoma. Translational Oncology. 13. 100816. 10.1016/j.tranon.2020.100816.

Sarfraz, Muhammad. Afzal, Attia. Khattak, Saadullah. Saddozai, Umair. Li, Hui-Min. Zhang, Qian-Qian. Madni, Muhammad Asadullah. Haleem, Kashif. Wu, Dongdong. Ji, Shao-Ping and Ji, Xin-Ying. (2020). Multifaceted behavior of PEST sequence enriched nuclear proteins in cancer biology and role in gene therapy. Journal of Cellular Physiology. 10.1002/jcp.30011.

Saddozai, Umair. Wang, Fengling. Akbar, Muhammad. Yan, Zhongyi. Khattak, Saadullah. Xie, Longxiang. Lu, Zhang. Badar, Muhammad. Ji, Xinying.  Zhu, Wan. and Guo, Xiangqian (2019). Prognostic biomarkers, pathogenic studies and treatment of Merkel Cell Carcinoma. Journal of Advances in Health. 01. 221-226. 10.3724/SP.J.2640-8686.2019.0120.

Saddozai, Umair. Khattak, Saadullah. Abbas, Azhar. Khan, Faiz ali. Wu, Dongdong. Ji, Xin-Ying. He, Fei. Akbar, Muhammad. Badar, Muhammad. Khan, Muzammil. (2019). PCNP is a Novel Regulator of Neuroblastomas Cancer.

Saddozai, U. et al. “OSMCC: An online survival analysis tool for Merkel cell carcinoma.” Cancer Translational Medicine 5 (2019): 47 - 49.

Muhammad Usman Akbar, Saadullahkhattak, Umair Ali khan Saddozai, Rafiq Ahmad, Muhammad Badar, Shams- uz- Zaman, Muhammad Daud, Ikram Ali, Waqar Ahmad. Antibacterial activity of Azadirachta indica and Citrullus colocynthis against different microorganisms.
Int. J. Biosci. 12(6), 85-90, June 20