PCNP publications

1: Xu T, Wu K, Shi J, Ji L, Song X, Tao G, Zheng S, Zhang L, Jiang B. LINC00858 promotes colon cancer progression through activation of STAT3/5 signaling by recruiting transcription factor RAD21 to upregulate PCNP. Cell Death Discov. 2022 Apr 25;8(1):228. doi: 10.1038/s41420-022-00832-w. PMID: 35468892; PMCID: PMC9038718.

2: Khan NH, Chen HJ, Fan Y, Surfaraz M, Ahammad MF, Qin YZ, Shahid M, Virk R, Jiang E, Wu DD, Ji XY. Biology of PEST-Containing Nuclear Protein: A Potential Molecular Target for Cancer Research. Front Oncol. 2022 Feb 4;12:784597. doi: 10.3389/fonc.2022.784597. PMID: 35186732; PMCID: PMC8855108.

3: Han ZP, Yang Y, Chen HY, Zhong MY, Zhuang GH. TIPE2 and PCNP expression abnormalities in peripheral blood mononuclear cells associated with disease activity in rheumatoid arthritis: a meta-analysis. Eur Rev Med Pharmacol Sci. 2021 Feb;25(3):1242-1249. doi: 10.26355/eurrev_202102_24828. PMID: 33629294.

4: Dong P, Fu H, Chen L, Zhang S, Zhang X, Li H, Wu D, Ji X. PCNP promotes ovarian cancer progression by accelerating β-catenin nuclear accumulation and triggering EMT transition. J Cell Mol Med. 2020 Jul;24(14):8221-8235. doi: 10.1111/jcmm.15491. Epub 2020 Jun 16. PMID: 32548978; PMCID: PMC7348179.

5: Afzal A, Sarfraz M, Li GL, Ji SP, Duan SF, Khan NH, Wu DD, Ji XY. Taking a holistic view of PEST-containing nuclear protein (PCNP) in cancer biology. Cancer Med. 2019 Oct;8(14):6335-6343. doi: 10.1002/cam4.2465. Epub 2019 Sep 5. PMID: 31487123; PMCID: PMC6797571.

6: Wang DY, Hong Y, Chen YG, Dong PZ, Liu SY, Gao YR, Lu D, Li HM, Li T, Guo JC, He F, Ren XQ, Sun SY, Wu DD, Duan SF, Ji XY. PEST-containing nuclear protein regulates cell proliferation, migration, and invasion in lung adenocarcinoma. Oncogenesis. 2019 Mar 14;8(3):22. doi: 10.1038/s41389-019-0132-4. PMID: 30872582; PMCID: PMC6418141.

7: Wu DD, Gao YR, Li T, Wang DY, Lu D, Liu SY, Hong Y, Ning HB, Liu JP, Shang J, Shi JF, Wei JS, Ji XY. PEST-containing nuclear protein mediates the proliferation, migration, and invasion of human neuroblastoma cells through MAPK and PI3K/AKT/mTOR signaling pathways. BMC Cancer. 2018 May 2;18(1):499. doi: 10.1186/s12885-018-4391-9. PMID: 29716528; PMCID: PMC5930684.

8: Shi-Bai Z, Rui-Min L, Ying-Chuan S, Jie Z, Chao J, Can-Hua Y, Xi C, Wen-Wei Q. TIPE2 expression is increased in peripheral blood mononuclear cells from patients with rheumatoid arthritis. Oncotarget. 2017 Sep 23;8(50):87472-87479. doi: 10.18632/oncotarget.21267. PMID: 29152095; PMCID: PMC5675647.

9: Arnesen T, Starheim KK, Van Damme P, Evjenth R, Dinh H, Betts MJ, Ryningen A, Vandekerckhove J, Gevaert K, Anderson D. The chaperone-like protein HYPK acts together with NatA in cotranslational N-terminal acetylation and prevention of Huntingtin aggregation. Mol Cell Biol. 2010 Apr;30(8):1898-909. doi: 10.1128/MCB.01199-09. Epub 2010 Feb 12. PMID: 20154145; PMCID: PMC2849469.

10: Mori T, Li Y, Hata H, Kochi H. NIRF is a ubiquitin ligase that is capable of ubiquitinating PCNP, a PEST-containing nuclear protein. FEBS Lett. 2004 Jan 16;557(1-3):209-14. doi: 10.1016/s0014-5793(03)01495-9. PMID: 14741369.

11: Mori T, Li Y, Hata H, Ono K, Kochi H. NIRF, a novel RING finger protein, is involved in cell-cycle regulation. Biochem Biophys Res Commun. 2002 Aug 23;296(3):530-6. doi: 10.1016/s0006-291x(02)00890-2. PMID: 12176013.

12:Li T, Li WY, Bai HL, Ma HB, Zhang H, Zhu JM, Li XH, Huang HY, Ma YF, Ji XY. The genetic profiling of preferentially expressed genes in murine splenic CD8α+ dendritic cells. Immunol Res. 2011 Oct;51(1):80-96. doi: 10.1007/s12026-011-8237-7. PMID: 21814860.

13:Nazeer Hussain Khan ,Muhammad Shahid ,Wenkang Wang ,Saadullah Khatak ,Ebenezeri Erasto Ngowi ,Salma S. Mahmoud ,Hao-Jie Chen ,Lei Qian ,Yangzhe Qin ,Tao Li ,Muhammad Zubair ,Shazrul Fazry ,Dong-Dong Wu ,Chun Yang Zhang ,Xin-Ying Ji. Structural, functional, phylogenetic, and molecular dynamic simulation study of PEST-containing nuclear protein: An e-science view. GPD 2022, 1(1), 65.

14: Arnesen T, Starheim KK, Van Damme P, Evjenth R, Dinh H, Betts MJ, Ryningen A, Vandekerckhove J, Gevaert K, Anderson D. The chaperone-like protein HYPK acts together with NatA in cotranslational N-terminal acetylation and prevention of Huntingtin aggregation. Mol Cell Biol. 2010 Apr;30(8):1898-909. doi: 10.1128/MCB.01199-09. Epub 2010 Feb 12. PMID: 20154145; PMCID: PMC2849469.

15:Chen YG, Liu HX, Hong Y, Dong PZ, Liu SY, Gao YR, Lu D, Li T, Wang DY, Wu DD, Ji XY. PCNP is a novel regulator of proliferation, migration, and invasion in human thyroid cancer. Int J Biol Sci 2022; 18(9):3605-3620. doi:10.7150/ijbs.70394.